This pharmacy textbook examines how the physicochemical properties of a drug, the dosage form in which the drug is given, and the route of administration influence the rate and extent of systemic drug absorption. The authors model the pharmacokinetics of drugs following both intravenous drug administration and extravascular delivery, and consider their role in drug product design. The fifth edition adds chapters on pharmacogenetics and the impact of drug product quality and biopharmaceutics on clinical efficacy. Annotation ©2004 Book News, Inc., Portland, OR

Leon Shargel, PhD is vice president of biopharmaceutics at Eon Labs, Inc. Wilson, NC., Susanna Wu-Pong, PhD, RPh is an associate professor in the department of pharmaceutics at Virginia Commonwealth University, Richmond, Virginia, Andrew B.C. Yu,PhD, RPh, formerly a professor at the Albany College of Pharmacy, is currently with the FDA in Rockville, MD.

Tags: applied biopharmaceutics pharmacokinetics