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Though always hoping that new strategies for treating asthma will be found, researchers from Europe, North America, and Australia report on continuing improvement in the effects of glucocoricoids, the most successful approach so far. Probably the most important development has been targeting inhaled medications to the lungs. After a pharmacologist's overview, they cover how inhaled corticosteroids have changed asthma therapy, side effects, molecular aspects of steroid action, determinants of airway-lung selectivity, the selectivity of current inhaled steroids, in-vivo research on selectivity, and future challenges. Annotation c. Book News, Inc., Portland, OR (booknews.com) More Reviews and Recommendations
Schleimer, Robert P., PhD; O'Byrne, Paul M., MB, FRCPI, FRCP (C); Szefler, Stanley J., MD; Brattsand, Ralph, PhD