In these twenty-three papers, molecular and cell biologists, pharmacologists, and pharmaceutical chemists describe their best methods for preparing, handling, and characterizing gene delivery agents, and for gene delivery itself. They examine several of the compounds which can be used to bind with DNA and form compact complexes facilitating cellular delivery. They also describe specific methods of transferring genes in vivo, including direct delivery by intratumoral injection and indirect delivery by cell-specific targeting of DNA complexes. Spectroscopic techniques for characterizing nonviral gene delivery agents are detailed. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Findeis, Mark A.

Tags: nonviral vectors for gene therapy